Possible Duplicate:
Do SSDs suffer from fragmentation?Is there an advantage to it? I mean, SSD is essentially random access memory.
Solution:
You said it yourself, SSDs are random access. Defragmenting them, as such, provides no benefit, but also wears down the drive by performing a lot of writes. Most modern OS’ turn automatic defragmentation off when you’re using an SSD, so just don’t do it manually and you should be fine.