If you install and use a desktop edition hard drive connected to a RAID controller, the hard drive may not work correctly. This is caused by the normal error recovery procedure that a desktop edition hard drive uses.
When an error is found on a desktop edition hard drive, the drive will enter into a deep recovery cycle to attempt to repair the error, recover the data from the problematic area, and then reallocate a dedicated area to replace the problematic area. This process can take up to 2 minutes depending on the severity of the issue. Most RAID controllers allow a very short amount of time for a hard drive to recover from an error. If a hard drive takes too long to complete this process, the hard drive will be dropped from the RAID array. Most RAID controllers allow from 7 to 15 seconds for error recovery before dropping a hard drive from an array. So it is not recommend installing desktop edition hard drives in an enterprise environment (on a RAID controller).
Western Digital RAID edition hard drives have a feature called TLER (Time Limited Error Recovery) which stops the hard drive from entering into a deep recovery cycle. The hard drive will only spend 7 seconds to attempt to recover. This means that the hard drive will not be dropped from a RAID array. While TLER is designed for RAID environments, a drive with TLER enabled will work with no performance decrease when used in non-RAID environments.
Note: There are a few cases where the manufacturer of the RAID controller have designed their drives to work with specific model Desktop drives. If this is the case you would need to contact the manufacturer of that controller for any support on that drive while it is used in a RAID environment.